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Epigenetic Studies Revealed a Ghost Proteome in PC1/3 KD Macrophages under Antitumoral Resistance Induced by IL-10

[Image: see text] Our previous investigation on macrophages has allowed us to show that the inhibition of the enzyme proprotein convertase (PC1/3) controls the activation of macrophages. We demonstrated that PC1/3 knockdown (KD) in macrophages exhibits an increased secretion of proinflammatory and a...

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Detalles Bibliográficos
Autores principales: Cardon, Tristan, Ozcan, Bilgehan, Aboulouard, Soulaimane, Kobeissy, Firas, Duhamel, Marie, Rodet, Franck, Fournier, Isabelle, Salzet, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643081/
https://www.ncbi.nlm.nih.gov/pubmed/33163760
http://dx.doi.org/10.1021/acsomega.0c02530