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SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts

Alterations of RNA homeostasis can lead to severe pathological conditions. The Survival of Motor Neuron (SMN) protein, which is reduced in Spinal Muscular Atrophy, impacts critical aspects of the RNA life cycle, such as splicing, trafficking, and translation. Increasing evidence points to a potentia...

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Detalles Bibliográficos
Autores principales: Gabanella, Francesca, Onori, Annalisa, Ralli, Massimo, Greco, Antonio, Passananti, Claudio, Di Certo, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643083/
https://www.ncbi.nlm.nih.gov/pubmed/33149163
http://dx.doi.org/10.1038/s41598-020-76174-3