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SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts
Alterations of RNA homeostasis can lead to severe pathological conditions. The Survival of Motor Neuron (SMN) protein, which is reduced in Spinal Muscular Atrophy, impacts critical aspects of the RNA life cycle, such as splicing, trafficking, and translation. Increasing evidence points to a potentia...
Autores principales: | Gabanella, Francesca, Onori, Annalisa, Ralli, Massimo, Greco, Antonio, Passananti, Claudio, Di Certo, Maria Grazia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643083/ https://www.ncbi.nlm.nih.gov/pubmed/33149163 http://dx.doi.org/10.1038/s41598-020-76174-3 |
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