Investigation of associations between Piezo1 mechanoreceptor gain-of-function variants and glaucoma-related phenotypes in humans and mice

Glaucoma disproportionately affects individuals of African descent. Prior studies of the PIEZO1 mechanoreceptor have suggested a possible role in glaucoma pathophysiology. Here, we investigated associations between a Piezo1 gain-of-function variant common in individuals of African descent with glauc...

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Detalles Bibliográficos
Autores principales: Baxter, Sally L., Keenan, William T., Athanas, Argus J., Proudfoot, James A., Zangwill, Linda M., Ayyagari, Radha, Liebmann, Jeffrey M., Girkin, Christopher A., Patapoutian, Ardem, Weinreb, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643131/
https://www.ncbi.nlm.nih.gov/pubmed/33149214
http://dx.doi.org/10.1038/s41598-020-76026-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643131/
https://www.ncbi.nlm.nih.gov/pubmed/33149214
http://dx.doi.org/10.1038/s41598-020-76026-0

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