Discovery and Structural Analysis to Improve the Enantioselectivity of Hydroxynitrile Lyase from Parafontaria laminata Millipedes for (R)-2-Chloromandelonitrile Synthesis

[Image: see text] Hydroxynitrile lyase (HNL) catalyzes the reversible synthesis and degradation of cyanohydrins, which are important synthetic intermediates for fine chemical and pharmaceutical industries. Here, we report the discovery of HNL from Parafontaria laminata (PlamHNL) millipedes, purifica...

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Detalles Bibliográficos
Autores principales: Nuylert, Aem, Nakabayashi, Makoto, Yamaguchi, Takuya, Asano, Yasuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643134/
https://www.ncbi.nlm.nih.gov/pubmed/33163773
http://dx.doi.org/10.1021/acsomega.0c03070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643134/
https://www.ncbi.nlm.nih.gov/pubmed/33163773
http://dx.doi.org/10.1021/acsomega.0c03070

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