Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons

The chromatin landscape of human brain cells encompasses key information to understanding brain function. Here we use ATAC-seq to profile the chromatin structure in four distinct populations of cells (glutamatergic neurons, GABAergic neurons, oligodendrocytes, and microglia/astrocytes) from three di...

Descripción completa

Detalles Bibliográficos
Autores principales: Hauberg, Mads E., Creus-Muncunill, Jordi, Bendl, Jaroslav, Kozlenkov, Alexey, Zeng, Biao, Corwin, Chuhyon, Chowdhury, Sarah, Kranz, Harald, Hurd, Yasmin L., Wegner, Michael, Børglum, Anders D., Dracheva, Stella, Ehrlich, Michelle E., Fullard, John F., Roussos, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643171/
https://www.ncbi.nlm.nih.gov/pubmed/33149216
http://dx.doi.org/10.1038/s41467-020-19319-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643171/
https://www.ncbi.nlm.nih.gov/pubmed/33149216
http://dx.doi.org/10.1038/s41467-020-19319-2

Ejemplares similares