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Aging and leukemic evolution of hematopoietic stem cells under various stress conditions
Hematopoietic stem cells (HSCs) have self-renewal capacity and differentiation potential into all lineages of blood cells throughout the lifetime of an organism. The function of HSCs gradually changes during aging. To date, various stress factors influencing HSC aging have been identified. The incre...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643313/ https://www.ncbi.nlm.nih.gov/pubmed/33292805 http://dx.doi.org/10.1186/s41232-020-00138-3 |