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Aging and leukemic evolution of hematopoietic stem cells under various stress conditions

Hematopoietic stem cells (HSCs) have self-renewal capacity and differentiation potential into all lineages of blood cells throughout the lifetime of an organism. The function of HSCs gradually changes during aging. To date, various stress factors influencing HSC aging have been identified. The incre...

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Detalles Bibliográficos
Autores principales: Kurosawa, Shuhei, Iwama, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643313/
https://www.ncbi.nlm.nih.gov/pubmed/33292805
http://dx.doi.org/10.1186/s41232-020-00138-3