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Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types

BACKGROUND: It is a long established fact that sex is an important factor that influences the transcriptional regulatory processes of an organism. However, understanding sex-based differences in gene expression has been limited because existing studies typically sequence and analyze bulk tissue from...

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Detalles Bibliográficos
Autores principales: Lu, Tianyuan, Mar, Jessica C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643324/
https://www.ncbi.nlm.nih.gov/pubmed/33153500
http://dx.doi.org/10.1186/s13293-020-00335-2