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Cerebral amyloid angiopathy aggravates perivascular clearance impairment in an Alzheimer’s disease mouse model

Cerebral amyloid angiopathy (CAA), defined as the accumulation of amyloid-beta (Aβ) on the vascular wall, is a major pathology of Alzheimer’s disease (AD) and has been thought to be caused by the failure of Aβ clearance. Although two types of perivascular clearance mechanisms, intramural periarteria...

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Detalles Bibliográficos
Autores principales: Kim, Shin Heun, Ahn, Ji Hoon, Yang, Hyunwoo, Lee, Peter, Koh, Gou Young, Jeong, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643327/
https://www.ncbi.nlm.nih.gov/pubmed/33153499
http://dx.doi.org/10.1186/s40478-020-01042-0