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Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy

BACKGROUND: Placenta-derived mesenchymal stem cells (PD-MSCs) have unique immunomodulatory properties. Phosphatase of regenerating liver-1 (PRL-1) regulates the self-renewal ability of stem cells and promotes proliferation. Graves’ ophthalmopathy (GO) is an autoimmune inflammatory disease of the orb...

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Detalles Bibliográficos
Autores principales: Kim, Jae Yeon, Park, Sohae, Lee, Hyun-Jung, Lew, Helen, Kim, Gi Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643360/
https://www.ncbi.nlm.nih.gov/pubmed/33153489
http://dx.doi.org/10.1186/s13287-020-01982-3