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Consecutive intra-gingival injections of lipopolysaccharide and butyric acid to mice induce abnormal behavior and changes in cytokine concentrations

BACKGROUND: Periodontopathic bacteria such as Porphyromonas gingivalis produce several metabolites, including lipopolysaccharide (LPS) and n-butyric acid (BA). Past work suggested that periodontal infection may cause cognitive impairment in mice. AIMS: To elucidate the mechanisms by which metabolite...

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Detalles Bibliográficos
Autores principales: Tsukahara, Takamitsu, Toyoda, Atsushi, Kawase, Takahiro, Nakamura, Shin-ichi, Ochiai, Kuniyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643404/
https://www.ncbi.nlm.nih.gov/pubmed/33153485
http://dx.doi.org/10.1186/s12974-020-02008-8