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Consecutive intra-gingival injections of lipopolysaccharide and butyric acid to mice induce abnormal behavior and changes in cytokine concentrations
BACKGROUND: Periodontopathic bacteria such as Porphyromonas gingivalis produce several metabolites, including lipopolysaccharide (LPS) and n-butyric acid (BA). Past work suggested that periodontal infection may cause cognitive impairment in mice. AIMS: To elucidate the mechanisms by which metabolite...
Autores principales: | Tsukahara, Takamitsu, Toyoda, Atsushi, Kawase, Takahiro, Nakamura, Shin-ichi, Ochiai, Kuniyasu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643404/ https://www.ncbi.nlm.nih.gov/pubmed/33153485 http://dx.doi.org/10.1186/s12974-020-02008-8 |
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