Low-density lipoprotein receptor (LDLR) regulates NLRP3-mediated neuronal pyroptosis following cerebral ischemia/reperfusion injury

BACKGROUND: Inflammatory response has been recognized as a pivotal pathophysiological process during cerebral ischemic stroke. NLRP3 inflammasome, involved in the regulation of inflammatory cascade, can simultaneously lead to GSDMD-executed pyroptosis in cerebral ischemia. Low-density lipoprotein re...

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Detalles Bibliográficos
Autores principales: Sun, Rui, Peng, Mengna, Xu, Pengfei, Huang, Feihong, Xie, Yi, Li, Juanji, Hong, Ye, Guo, Hongquan, Liu, Qian, Zhu, Wusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643474/
https://www.ncbi.nlm.nih.gov/pubmed/33153475
http://dx.doi.org/10.1186/s12974-020-01988-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643474/
https://www.ncbi.nlm.nih.gov/pubmed/33153475
http://dx.doi.org/10.1186/s12974-020-01988-x

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