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Low-density lipoprotein receptor (LDLR) regulates NLRP3-mediated neuronal pyroptosis following cerebral ischemia/reperfusion injury

BACKGROUND: Inflammatory response has been recognized as a pivotal pathophysiological process during cerebral ischemic stroke. NLRP3 inflammasome, involved in the regulation of inflammatory cascade, can simultaneously lead to GSDMD-executed pyroptosis in cerebral ischemia. Low-density lipoprotein re...

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Detalles Bibliográficos
Autores principales:	Sun, Rui, Peng, Mengna, Xu, Pengfei, Huang, Feihong, Xie, Yi, Li, Juanji, Hong, Ye, Guo, Hongquan, Liu, Qian, Zhu, Wusheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643474/ https://www.ncbi.nlm.nih.gov/pubmed/33153475 http://dx.doi.org/10.1186/s12974-020-01988-x

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