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Colesevelam enhances the beneficial effects of brown fat activation on hyperlipidaemia and atherosclerosis development

AIMS: Brown fat activation accelerates the uptake of cholesterol-enriched remnants by the liver and thereby lowers plasma cholesterol, consequently protecting against atherosclerosis development. Hepatic cholesterol is then converted into bile acids (BAs) that are secreted into the intestine and lar...

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Detalles Bibliográficos
Autores principales: Zhou, Enchen, Hoeke, Geerte, Li, Zhuang, Eibergen, Arthur C, Schonk, Amber W, Koehorst, Martijn, Boverhof, Renze, Havinga, Rick, Kuipers, Folkert, Coskun, Tamer, Boon, Mariëtte R, Groen, Albert K, Rensen, Patrick C N, Berbée, Jimmy F P, Wang, Yanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643538/
https://www.ncbi.nlm.nih.gov/pubmed/31589318
http://dx.doi.org/10.1093/cvr/cvz253