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Colesevelam enhances the beneficial effects of brown fat activation on hyperlipidaemia and atherosclerosis development
AIMS: Brown fat activation accelerates the uptake of cholesterol-enriched remnants by the liver and thereby lowers plasma cholesterol, consequently protecting against atherosclerosis development. Hepatic cholesterol is then converted into bile acids (BAs) that are secreted into the intestine and lar...
Autores principales: | Zhou, Enchen, Hoeke, Geerte, Li, Zhuang, Eibergen, Arthur C, Schonk, Amber W, Koehorst, Martijn, Boverhof, Renze, Havinga, Rick, Kuipers, Folkert, Coskun, Tamer, Boon, Mariëtte R, Groen, Albert K, Rensen, Patrick C N, Berbée, Jimmy F P, Wang, Yanan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643538/ https://www.ncbi.nlm.nih.gov/pubmed/31589318 http://dx.doi.org/10.1093/cvr/cvz253 |
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