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Intra‐CSF topotecan in treatment of breast cancer patients with leptomeningeal metastases

BACKGROUND: There are few treatment options for patients with leptomeningeal metastases (LM). METHODS: We report a case series of patients with breast cancer and LM treated with intra‐CSF topotecan (TOPO). Outcome was assessed by clinical exam and MRI at baseline, at end of induction (4‐5 weeks), th...

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Detalles Bibliográficos
Autores principales: Jaeckle, Kurt A., Dixon, Jesse G., Anderson, Stephen Keith, Moreno‐Aspitia, Alvaro, Colon‐Otero, Gerardo, Hebenstreit, Kathy, Patel, Tejal A., Reddy, Samarth L., Perez, Edith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643683/
https://www.ncbi.nlm.nih.gov/pubmed/32885617
http://dx.doi.org/10.1002/cam4.3422