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Model-Based Meta-analysis of Rifampicin Exposure and Mortality in Indonesian Tuberculous Meningitis Trials

BACKGROUND: Intensified antimicrobial treatment with higher rifampicin doses may improve outcome of tuberculous meningitis, but the desirable exposure and necessary dose are unknown. Our objective was to characterize the relationship between rifampicin exposures and mortality in order to identify op...

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Detalles Bibliográficos
Autores principales: Svensson, Elin M, Dian, Sofiati, Te Brake, Lindsey, Ganiem, Ahmad Rizal, Yunivita, Vycke, van Laarhoven, Arjan, Van Crevel, Reinout, Ruslami, Rovina, Aarnoutse, Rob E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643733/
https://www.ncbi.nlm.nih.gov/pubmed/31665299
http://dx.doi.org/10.1093/cid/ciz1071