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Randomized Controlled Crossover Trials of the Pharmacokinetics of PRC-063, a Novel Multilayer Extended-Release Formulation of Methylphenidate, in Healthy Adults

PURPOSE/BACKGROUND: PRC-063 is a once-daily, extended-release oral formulation of methylphenidate hydrochloride developed to provide early and prolonged symptom improvement in patients with attention-deficit/hyperactivity disorder. METHODS/PROCEDURES: We conducted 3 randomized, open-label crossover...

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Detalles Bibliográficos
Autores principales: Katzman, Martin A., Mattingly, Greg, Klassen, Larry J., Cataldo, Marc J., Donnelly, Graeme A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643797/
https://www.ncbi.nlm.nih.gov/pubmed/33009228
http://dx.doi.org/10.1097/JCP.0000000000001277