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Activin Receptor-Ligand Trap for the Treatment of β-thalassemia: A Serendipitous Discovery
β-thalassemia is a hereditary disorder caused by defective production of β-globin chains of hemoglobin (Hb) that leads to an increased α/β globins ratio with subsequent free α-globins. Alpha globin excess causes oxidative stress, red blood cells membrane damage, premature death of late-stage erythro...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Università Cattolica del Sacro Cuore
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643807/ https://www.ncbi.nlm.nih.gov/pubmed/33194149 http://dx.doi.org/10.4084/MJHID.2020.075 |