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Maternal dysglycaemia, changes in the infant’s epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial
BACKGROUND: Higher maternal plasma glucose (PG) concentrations, even below gestational diabetes mellitus (GDM) thresholds, are associated with adverse offspring outcomes, with DNA methylation proposed as a mediating mechanism. Here, we examined the relationships between maternal dysglycaemia at 24 t...
Autores principales: | Antoun, Elie, Kitaba, Negusse T., Titcombe, Philip, Dalrymple, Kathryn V., Garratt, Emma S., Barton, Sheila J., Murray, Robert, Seed, Paul T., Holbrook, Joanna D., Kobor, Michael S., Lin, David TS, MacIsaac, Julia L., Burdge, Graham C., White, Sara L., Poston, Lucilla, Godfrey, Keith M., Lillycrop, Karen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643947/ https://www.ncbi.nlm.nih.gov/pubmed/33151971 http://dx.doi.org/10.1371/journal.pmed.1003229 |
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