Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis

Sepsis is the leading cause of death in hospitalized patients and beyond the hospital stay and these long-term sequelae are due in part to unresolved inflammation. Metabolic shift from oxidative phosphorylation to aerobic glycolysis links metabolism to inflammation and such a shift is commonly obser...

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Detalles Bibliográficos
Autores principales: Bakalov, Veli, Reyes-Uribe, Laura, Deshpande, Rahul, Maloy, Abigail L., Shapiro, Steven D., Angus, Derek C., Chang, Chung-Chou H., Le Moyec, Laurence, Wendell, Stacy Gelhaus, Kaynar, Ata Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643993/
https://www.ncbi.nlm.nih.gov/pubmed/33151963
http://dx.doi.org/10.1371/journal.pone.0241122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643993/
https://www.ncbi.nlm.nih.gov/pubmed/33151963
http://dx.doi.org/10.1371/journal.pone.0241122

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