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Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis
Sepsis is the leading cause of death in hospitalized patients and beyond the hospital stay and these long-term sequelae are due in part to unresolved inflammation. Metabolic shift from oxidative phosphorylation to aerobic glycolysis links metabolism to inflammation and such a shift is commonly obser...
Autores principales: | Bakalov, Veli, Reyes-Uribe, Laura, Deshpande, Rahul, Maloy, Abigail L., Shapiro, Steven D., Angus, Derek C., Chang, Chung-Chou H., Le Moyec, Laurence, Wendell, Stacy Gelhaus, Kaynar, Ata Murat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643993/ https://www.ncbi.nlm.nih.gov/pubmed/33151963 http://dx.doi.org/10.1371/journal.pone.0241122 |
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