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High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer

BACKGROUND: Antiangiogenic therapy, although part of standard treatment in ovarian cancer, has variable efficacy. Furthermore, little is known about the prognostic biomarkers and factors influencing angiogenesis in cancer tissue. We evaluated the expression of angiopoietin-2 and two endothelial tyro...

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Detalles Bibliográficos
Autores principales: Sopo, Minna, Sallinen, Hanna, Hämäläinen, Kirsi, Kivelä, Annukka, Ylä-Herttuala, Seppo, Kosma, Veli-Matti, Keski-Nisula, Leea, Anttila, Maarit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644024/
https://www.ncbi.nlm.nih.gov/pubmed/33151982
http://dx.doi.org/10.1371/journal.pone.0241484