Cargando…

High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer

BACKGROUND: Antiangiogenic therapy, although part of standard treatment in ovarian cancer, has variable efficacy. Furthermore, little is known about the prognostic biomarkers and factors influencing angiogenesis in cancer tissue. We evaluated the expression of angiopoietin-2 and two endothelial tyro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sopo, Minna, Sallinen, Hanna, Hämäläinen, Kirsi, Kivelä, Annukka, Ylä-Herttuala, Seppo, Kosma, Veli-Matti, Keski-Nisula, Leea, Anttila, Maarit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644024/ https://www.ncbi.nlm.nih.gov/pubmed/33151982 http://dx.doi.org/10.1371/journal.pone.0241484

Ejemplares similares

Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer
por: Sopo, Minna, et al.
Publicado: (2019)

Primary and metastatic ovarian cancer: Characterization by 3.0T diffusion-weighted MRI
por: Lindgren, Auni, et al.
Publicado: (2017)

Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer
por: Sallinen, Hanna, et al.
Publicado: (2014)

Robotic-assisted laparoscopy is a feasible method for resection of deep infiltrating endometriosis, especially in the rectosigmoid area
por: Hiltunen, Janika, et al.
Publicado: (2021)

Expression of Hyaluronan Synthases (HAS1–3) and Hyaluronidases (HYAL1–2) in Serous Ovarian Carcinomas: Inverse Correlation between HYAL1 and Hyaluronan Content
por: Nykopp, Timo K, et al.
Publicado: (2009)

Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma
por: Nykopp, Timo K, et al.
Publicado: (2010)

Parental smoking and cessation during pregnancy and the risk of childhood asthma
por: Harju, Maijakaisa, et al.
Publicado: (2016)

AAV8-mediated sVEGFR2 and sVEGFR3 gene therapy combined with chemotherapy reduces the growth and microvasculature of human ovarian cancer and prolongs the survival in mice
por: Kujala, Anni, et al.
Publicado: (2022)

Nuclear expression of Snail1 in borderline and malignant epithelial ovarian tumours is associated with tumour progression
por: Tuhkanen, Hanna, et al.
Publicado: (2009)

Dynamic contrast-enhanced perfusion parameters in ovarian cancer: Good accuracy in identifying high HIF-1α expression
por: Lindgren, Auni, et al.
Publicado: (2019)

High estradiol levels during a long agonist IVF protocol are associated with decreased food intake, higher leptin concentrations, and lower levels of high-sensitivity C-reactive protein
por: Leppänen, Jonna, et al.
Publicado: (2023)

Maternal socioeconomic status and the risk of asthma among offspring
por: Harju, Maijakaisa, et al.
Publicado: (2015)

Dotted collar placed around carotid artery induces asymmetric neointimal lesion formation in rabbits without intravascular manipulations
por: Kivelä, Antti, et al.
Publicado: (2012)

Increased risk of preeclampsia after use of paracetamol during pregnancy – causal or coincidence?
por: von Hellens, Hetti, et al.
Publicado: (2021)

The effect of different estradiol levels on carotid artery distensibility during a long agonist IVF protocol
por: Leppänen, Jonna, et al.
Publicado: (2020)

Self‐reported alcohol consumption of pregnant women and their partners correlates both before and during pregnancy: A cohort study with 21,472 singleton pregnancies
por: Voutilainen, Taija, et al.
Publicado: (2022)

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization
por: Kaikkonen, Minna U., et al.
Publicado: (2014)

Infertility Treatment and Umbilical Cord Length–Novel Markers of Childhood Epilepsy?
por: Räisänen, Sari, et al.
Publicado: (2013)

Etiology, syndrome diagnosis, and cognition in childhood‐onset epilepsy: A population‐based study
por: Sokka, Arja, et al.
Publicado: (2017)

Environmental Intolerance, Symptoms and Disability Among Fertile-Aged Women
por: Vuokko, Aki, et al.
Publicado: (2018)

High baseline Tie1 level predicts poor survival in metastatic breast cancer
por: Tiainen, Leena, et al.
Publicado: (2019)

Comparative transcriptome analysis of matched primary and distant metastatic ovarian carcinoma
por: Sallinen, H., et al.
Publicado: (2019)

Vulvovaginal yeast infections, gestational diabetes and pregnancy outcome
por: Blomberg, Leeni, et al.
Publicado: (2023)

Caffeine content in newborn hair correlates with maternal dietary intake
por: Lehtonen, Anni, et al.
Publicado: (2020)

Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling
por: Toivanen, Pyry I., et al.
Publicado: (2017)

Gene Therapy Used in Cancer Treatment
por: Wirth, Thomas, et al.
Publicado: (2014)

Therapeutic Potential of VEGF-B in Coronary Heart Disease and Heart Failure: Dream or Vision?
por: Mallick, Rahul, et al.
Publicado: (2022)

Long-term safety and efficacy of intramyocardial adenovirus-mediated VEGF-D(ΔNΔC) gene therapy eight-year follow-up of phase I KAT301 study
por: Leikas, Aleksi J., et al.
Publicado: (2021)

The TIE Receptor Family
por: Saharinen, Pipsa, et al.
Publicado: (2015)

Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice
por: Dijkstra, M. H., et al.
Publicado: (2014)

Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance T(RAFFn), T(1ρ) and T(2) relaxation times
por: Ylä-Herttuala, Elias, et al.
Publicado: (2023)

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction
por: Vuorio, Taina, et al.
Publicado: (2018)

Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success
por: Dragneva, Galina, et al.
Publicado: (2013)

Characterization of a new IN-I-PpoI fusion protein and a homology-arm containing transgene cassette that improve transgene expression persistence and 28S rRNA gene-targeted insertion of lentiviral vectors
por: Nousiainen, Alisa, et al.
Publicado: (2023)

The human placental proteome is affected by maternal smoking
por: Huuskonen, Pasi, et al.
Publicado: (2016)

Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function
por: Jauhiainen, Suvi, et al.
Publicado: (2019)

A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus
por: Husso, Tiia, et al.
Publicado: (2014)

Nucleic Acid–Based Therapies for Atherosclerosis
por: Mäkinen, Petri, et al.
Publicado: (2020)

Novel RNAi-Based Therapies for Atherosclerosis
por: Ruotsalainen, Anna-Kaisa, et al.
Publicado: (2021)

Kuopio birth cohort – design of a Finnish joint research effort for identification of environmental and lifestyle risk factors for the wellbeing of the mother and the newborn child
por: Huuskonen, Pasi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_6h3b3tuejfddjtvsipva2j69st