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Yap activation in irradiated parotid salivary glands is regulated by ROCK activity

Radiotherapy plays a major role in the curative treatment of head and neck cancer, either as a single modality therapy, or in combination with surgery or chemotherapy, or both. Despite advances to limit radiation-induced side-effects, the major salivary glands are often affected. This frequently lea...

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Detalles Bibliográficos
Autores principales: Wong, Wen Yu, Gilman, Kristy, Limesand, Kirsten H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644026/
https://www.ncbi.nlm.nih.gov/pubmed/33151927
http://dx.doi.org/10.1371/journal.pone.0232921