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High prevalence and extended deletions in Plasmodium falciparum hrp2/3 genomic loci in Ethiopia

Deletions in Plasmodium falciparum histidine rich protein 2(pfhrp2) gene threaten the usefulness of the most widely used HRP2-based malaria rapid diagnostic tests (mRDTs) that cross react with its structural homologue, PfHRP3. Parasites with deleted pfhrp2/3 genes remain undetected and untreated due...

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Detalles Bibliográficos
Autores principales: Golassa, Lemu, Messele, Alebachew, Amambua-Ngwa, Alfred, Swedberg, Gote
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644029/
https://www.ncbi.nlm.nih.gov/pubmed/33152025
http://dx.doi.org/10.1371/journal.pone.0241807