Synthetic Lethal Drug Combinations Targeting Proteasome and Histone Deacetylase Inhibitors in TP53-Mutated Cancers

BACKGROUND: We have recently published SL-BioDP, a web resource for querying, exploration and visualization of potential synthetic lethal targets and possible synergistic drug combinations for 18 cancer types. METHODS: From our predictive synthetic lethality model used in SL-BioDP, we inferred TP53...

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Detalles Bibliográficos
Autores principales: Das, Shaoli, Deng, Xiang, Camphausen, Kevin, Shankavaram, Uma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644110/
https://www.ncbi.nlm.nih.gov/pubmed/33163985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644110/
https://www.ncbi.nlm.nih.gov/pubmed/33163985

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