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Trends of mutation accumulation across global SARS-CoV-2 genomes: Implications for the evolution of the novel coronavirus

To understand SARS-CoV-2 microevolution, this study explored the genome-wide frequency, gene-wise distribution, and molecular nature of all point-mutations detected across its 71,703 RNA-genomes deposited in GISAID till 21 August 2020. Globally, nsp1/nsp2 and orf7a/orf3a were the most mutation-ridde...

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Detalles Bibliográficos
Autores principales: Roy, Chayan, Mandal, Santi M., Mondal, Suresh K., Mukherjee, Shriparna, Mapder, Tarunendu, Ghosh, Wriddhiman, Chakraborty, Ranadhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644180/
https://www.ncbi.nlm.nih.gov/pubmed/33161087
http://dx.doi.org/10.1016/j.ygeno.2020.11.003