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Protection of outbred mice against a vaginal challenge by a Chlamydia trachomatis serovar E recombinant major outer membrane protein vaccine is dependent on phosphate substitution in the adjuvant

Chlamydia trachomatis is the most common bacterial sexually-transmitted pathogen for which there is no vaccine. We previously demonstrated that the degree of phosphate substitution in an aluminum hydroxide adjuvant in a TLR-4-based C. trachomatis serovar E (Ser E) recombinant major outer membrane pr...

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Detalles Bibliográficos
Autores principales: Pal, Sukumar, Ausar, Salvador Fernando, Tifrea, Delia F., Cheng, Chunmei, Gallichan, Scott, Sanchez, Violette, de la Maza, Luis M., Visan, Lucian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644203/
https://www.ncbi.nlm.nih.gov/pubmed/32118511
http://dx.doi.org/10.1080/21645515.2020.1717183