African Vegetables (Clerodendrum volubile Leaf and Irvingia gabonensis Seed Extracts) Effectively Mitigate Trastuzumab-Induced Cardiotoxicity in Wistar Rats

Trastuzumab (TZM) is a humanized monoclonal antibody that has been approved for the clinical management of HER2-positive metastatic breast and gastric cancers but its use is limited by its cumulative dose and off-target cardiotoxicity. Unfortunately, till date, there is no approved antidote to this...

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Detalles Bibliográficos
Autores principales: Olorundare, Olufunke, Adeneye, Adejuwon, Akinsola, Akinyele, Soyemi, Sunday, Mgbehoma, Alban, Okoye, Ikechukwu, Ntambi, James M., Mukhtar, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644299/
https://www.ncbi.nlm.nih.gov/pubmed/33178389
http://dx.doi.org/10.1155/2020/9535426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644299/
https://www.ncbi.nlm.nih.gov/pubmed/33178389
http://dx.doi.org/10.1155/2020/9535426

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