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Prokineticin 2 via Calcium-Sensing Receptor Activated NLRP3 Inflammasome Pathway in the Testicular Macrophages of Uropathogenic Escherichia coli-Induced Orchitis

Reproductive tract infections contribute to the development of testicular inflammatory lesions, leading to male infertility. Previous research shows that the activation of the NLRP3 inflammasome in orchitis promotes the secretion and maturation of IL-1β and, thus, decreases male fertility. The calci...

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Detalles Bibliográficos
Autores principales: Su, Yufang, Zhang, Yuan, Hu, Zhiyong, He, Liting, Wang, Wei, Xu, Jia, Fan, Zunpan, Liu, Chunyan, Zhang, Huiping, Zhao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644440/
https://www.ncbi.nlm.nih.gov/pubmed/33193351
http://dx.doi.org/10.3389/fimmu.2020.570872