Efferocytic Defects in Early Atherosclerosis Are Driven by GATA2 Overexpression in Macrophages

The loss of efferocytosis—the phagocytic clearance of apoptotic cells—is an initiating event in atherosclerotic plaque formation. While the loss of macrophage efferocytosis is a prerequisite for advanced plaque formation, the transcriptional and cellular events in the pre-lesion site that drive thes...

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Detalles Bibliográficos
Autores principales: Yin, Charles, Vrieze, Angela M., Rosoga, Mara, Akingbasote, James, Pawlak, Emily N., Jacob, Rajesh Abraham, Hu, Jonathan, Sharma, Neha, Dikeakos, Jimmy D., Barra, Lillian, Nagpal, A. Dave, Heit, Bryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644460/
https://www.ncbi.nlm.nih.gov/pubmed/33193444
http://dx.doi.org/10.3389/fimmu.2020.594136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644460/
https://www.ncbi.nlm.nih.gov/pubmed/33193444
http://dx.doi.org/10.3389/fimmu.2020.594136

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