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Efferocytic Defects in Early Atherosclerosis Are Driven by GATA2 Overexpression in Macrophages
The loss of efferocytosis—the phagocytic clearance of apoptotic cells—is an initiating event in atherosclerotic plaque formation. While the loss of macrophage efferocytosis is a prerequisite for advanced plaque formation, the transcriptional and cellular events in the pre-lesion site that drive thes...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644460/ https://www.ncbi.nlm.nih.gov/pubmed/33193444 http://dx.doi.org/10.3389/fimmu.2020.594136 |