Aberrant NSUN2-mediated m(5)C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma

RNA methylation is an important epigenetic modification. Recent studies on RNA methylation mainly focus on the m(6)A modification of mRNA, but very little is known about the m(5)C modification. NSUN2 is an RNA methyltransferase responsible for the m(5)C modification of multiple RNAs. In this study,...

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Detalles Bibliográficos
Autores principales: Sun, Zhen, Xue, Songlei, Zhang, Meiying, Xu, Hui, Hu, Xuming, Chen, Shihao, Liu, Yangyang, Guo, Mingzhou, Cui, Hengmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644462/
https://www.ncbi.nlm.nih.gov/pubmed/32978516
http://dx.doi.org/10.1038/s41388-020-01475-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644462/
https://www.ncbi.nlm.nih.gov/pubmed/32978516
http://dx.doi.org/10.1038/s41388-020-01475-w

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