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Aberrant NSUN2-mediated m(5)C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma
RNA methylation is an important epigenetic modification. Recent studies on RNA methylation mainly focus on the m(6)A modification of mRNA, but very little is known about the m(5)C modification. NSUN2 is an RNA methyltransferase responsible for the m(5)C modification of multiple RNAs. In this study,...
Autores principales: | Sun, Zhen, Xue, Songlei, Zhang, Meiying, Xu, Hui, Hu, Xuming, Chen, Shihao, Liu, Yangyang, Guo, Mingzhou, Cui, Hengmi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644462/ https://www.ncbi.nlm.nih.gov/pubmed/32978516 http://dx.doi.org/10.1038/s41388-020-01475-w |
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