Mfn2 Overexpression Attenuates Cardio-Cerebrovascular Ischemia–Reperfusion Injury Through Mitochondrial Fusion and Activation of the AMPK/Sirt3 Signaling

Mitochondria are potential targets for the treatment of cardio-cerebrovascular ischemia–reperfusion (I/R) injury. However, the role of the mitofusin 2 (Mfn2) protein in regulating mitochondrial fusion and cell survival has not been investigated. In the present study, an adenovirus-mediated Mfn2 over...

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Detalles Bibliográficos
Autores principales: Liu, Min, Li, Xiaoyang, Huang, Dezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644524/
https://www.ncbi.nlm.nih.gov/pubmed/33195281
http://dx.doi.org/10.3389/fcell.2020.598078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644524/
https://www.ncbi.nlm.nih.gov/pubmed/33195281
http://dx.doi.org/10.3389/fcell.2020.598078

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