Phosphodiesterase 10A Inhibition Leads to Brain Region-Specific Recovery Based on Stroke Type

Stroke is the leading cause of adult disability. Recovery of function after stroke involves signaling events that are mediated by cAMP and cGMP pathways, such as axonal sprouting, neurogenesis, and synaptic plasticity. cAMP and cGMP are degraded by phosphodiesterases (PDEs), which are differentially...

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Detalles Bibliográficos
Autores principales: Birjandi, Shirin Z., Abduljawad, Nora, Nair, Shyama, Dehghani, Morteza, Suzuki, Kazunori, Kimura, Haruhide, Carmichael, S. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644574/
https://www.ncbi.nlm.nih.gov/pubmed/32378029
http://dx.doi.org/10.1007/s12975-020-00819-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644574/
https://www.ncbi.nlm.nih.gov/pubmed/32378029
http://dx.doi.org/10.1007/s12975-020-00819-8

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