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Phosphodiesterase 10A Inhibition Leads to Brain Region-Specific Recovery Based on Stroke Type
Stroke is the leading cause of adult disability. Recovery of function after stroke involves signaling events that are mediated by cAMP and cGMP pathways, such as axonal sprouting, neurogenesis, and synaptic plasticity. cAMP and cGMP are degraded by phosphodiesterases (PDEs), which are differentially...
Autores principales: | Birjandi, Shirin Z., Abduljawad, Nora, Nair, Shyama, Dehghani, Morteza, Suzuki, Kazunori, Kimura, Haruhide, Carmichael, S. Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644574/ https://www.ncbi.nlm.nih.gov/pubmed/32378029 http://dx.doi.org/10.1007/s12975-020-00819-8 |
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