Amido-Bridged Nucleic Acid-Modified Antisense Oligonucleotides Targeting SYT13 to Treat Peritoneal Metastasis of Gastric Cancer

Patients with peritoneal metastasis of gastric cancer have dismal prognosis, mainly because of inefficient systemic delivery of drugs to peritoneal tumors. We aimed to develop an intraperitoneal treatment strategy using amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides (ASOs) tar...

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Detalles Bibliográficos
Autores principales: Kanda, Mitsuro, Kasahara, Yuuya, Shimizu, Dai, Miwa, Takashi, Umeda, Shinichi, Sawaki, Koichi, Nakamura, Shunsuke, Kodera, Yasuhiro, Obika, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644579/
https://www.ncbi.nlm.nih.gov/pubmed/33230476
http://dx.doi.org/10.1016/j.omtn.2020.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644579/
https://www.ncbi.nlm.nih.gov/pubmed/33230476
http://dx.doi.org/10.1016/j.omtn.2020.10.001

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