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Hypoxia-inducible factor-2α is crucial for proper brain development

Sufficient tissue oxygenation is required for regular brain function; thus oxygen supply must be tightly regulated to avoid hypoxia and irreversible cell damage. If hypoxia occurs the transcription factor complex hypoxia-inducible factor (HIF) will accumulate and coordinate adaptation of cells to hy...

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Detalles Bibliográficos
Autores principales: Kleszka, Kira, Leu, Tristan, Quinting, Theresa, Jastrow, Holger, Pechlivanis, Sonali, Fandrey, Joachim, Schreiber, Timm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644612/
https://www.ncbi.nlm.nih.gov/pubmed/33154420
http://dx.doi.org/10.1038/s41598-020-75838-4