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Targeting PSMD14 inhibits melanoma growth through SMAD3 stabilization

Although melanoma therapy is improved by novel molecular targeted reagents, including vemurafenib, aberrant proliferation and early metastasis remain obstacles for melanoma; therefore, novel target molecules for melanoma need to be identified. In this study, we focused on deubiquitinating enzymes, w...

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Detalles Bibliográficos
Autores principales: Yokoyama, Satoru, Iwakami, Yusuke, Hang, Zhao, Kin, Ryoei, Zhou, Yue, Yasuta, Yutaka, Takahashi, Atsushi, Hayakawa, Yoshihiro, Sakurai, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644625/
https://www.ncbi.nlm.nih.gov/pubmed/33154524
http://dx.doi.org/10.1038/s41598-020-76373-y