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A protein assembly mediates Xist localization and gene silencing
Nuclear compartments play diverse roles in regulating gene expression, yet the molecular forces and components driving compartment formation remain largely unclear(1). The long non-coding RNA Xist establishes an intra-chromosomal compartment by localizing at a high concentration in a territory spati...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644664/ https://www.ncbi.nlm.nih.gov/pubmed/32908311 http://dx.doi.org/10.1038/s41586-020-2703-0 |