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A protein assembly mediates Xist localization and gene silencing

Nuclear compartments play diverse roles in regulating gene expression, yet the molecular forces and components driving compartment formation remain largely unclear(1). The long non-coding RNA Xist establishes an intra-chromosomal compartment by localizing at a high concentration in a territory spati...

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Detalles Bibliográficos
Autores principales: Pandya-Jones, Amy, Markaki, Yolanda, Serizay, Jacques, Chitiashvili, Tsotne, Mancia, Walter, Damianov, Andrey, Chronis, Costantinos, Papp, Bernadett, Chen, Chun-Kan, McKee, Robin, Wang, Xiao-Jun, Chau, Anthony, Sabri, Shan, Leonhardt, Heinrich, Zheng, Sika, Guttman, Mitchell, Black, Douglas. L., Plath, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644664/
https://www.ncbi.nlm.nih.gov/pubmed/32908311
http://dx.doi.org/10.1038/s41586-020-2703-0