Targeted inhibition of glutamine metabolism enhances the antitumor effect of selumetinib in KRAS-mutant NSCLC

Regulated by the tumor microenvironment, the metabolic network of the tumor is reprogrammed, driven by oncogenes and tumor suppressor genes. The metabolic phenotype of tumors of different driven-genes and different tissue types is extremely heterogeneous. KRAS-mutant non-small cell lung cancer (NSCL...

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Detalles Bibliográficos
Autores principales: Xia, Meng, Li, Xuena, Diao, Yao, Du, Bulin, Li, Yaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644669/
https://www.ncbi.nlm.nih.gov/pubmed/33137541
http://dx.doi.org/10.1016/j.tranon.2020.100920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644669/
https://www.ncbi.nlm.nih.gov/pubmed/33137541
http://dx.doi.org/10.1016/j.tranon.2020.100920

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