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Structures of mouse DUOX1–DUOXA1 provide mechanistic insights into enzyme activation and regulation
DUOX1, a NADPH oxidase family member, catalyzes the production of hydrogen peroxide. DUOX1 is expressed in various tissues, including thyroid and respiratory tract, and plays a crucial role in processes such as thyroid hormone biosynthesis and innate host defense. DUOX1 co-assembles with its maturat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644671/ https://www.ncbi.nlm.nih.gov/pubmed/32929281 http://dx.doi.org/10.1038/s41594-020-0501-x |