Butyrate induced Tregs are capable of migration from the GALT to the pancreas to restore immunological tolerance during type-1 diabetes

Type-1 diabetes (T1D) is an autoimmune disease caused by progressive loss of insulin-producing beta cells in the pancreas. Butyrate is a commensal microbial-derived metabolite, implicated in intestinal homeostasis and immune regulation. Here, we investigated the mechanism of diabetes remission in no...

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Detalles Bibliográficos
Autores principales: Jacob, Neenu, Jaiswal, Shivani, Maheshwari, Deep, Nallabelli, Nayudu, Khatri, Neeraj, Bhatia, Alka, Bal, Amanjit, Malik, Vivek, Verma, Savita, Kumar, Rakesh, Sachdeva, Naresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644709/
https://www.ncbi.nlm.nih.gov/pubmed/33154424
http://dx.doi.org/10.1038/s41598-020-76109-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644709/
https://www.ncbi.nlm.nih.gov/pubmed/33154424
http://dx.doi.org/10.1038/s41598-020-76109-y

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