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N-acetylcysteine prevents olanzapine-induced oxidative stress in mHypoA-59 hypothalamic neurons

Olanzapine is a second-generation antipsychotic (AP) drug commonly prescribed for the treatment of schizophrenia. Recently, olanzapine has been found to cause brain tissue volume loss in rodent and primate studies; however, the underlying mechanism remains unknown. Abnormal autophagy and oxidative s...

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Detalles Bibliográficos
Autores principales: Boz, Zehra, Hu, Minmin, Yu, Yinghua, Huang, Xu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644715/
https://www.ncbi.nlm.nih.gov/pubmed/33154380
http://dx.doi.org/10.1038/s41598-020-75356-3