Phase separation by the polyhomeotic sterile alpha motif compartmentalizes Polycomb Group proteins and enhances their activity

Polycomb Group (PcG) proteins organize chromatin at multiple scales to regulate gene expression. A conserved Sterile Alpha Motif (SAM) in the Polycomb Repressive Complex 1 (PRC1) subunit Polyhomeotic (Ph) has been shown to play an important role in chromatin compaction and large-scale chromatin orga...

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Detalles Bibliográficos
Autores principales: Seif, Elias, Kang, Jin Joo, Sasseville, Charles, Senkovich, Olga, Kaltashov, Alexander, Boulier, Elodie L., Kapur, Ibani, Kim, Chongwoo A., Francis, Nicole J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644731/
https://www.ncbi.nlm.nih.gov/pubmed/33154383
http://dx.doi.org/10.1038/s41467-020-19435-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644731/
https://www.ncbi.nlm.nih.gov/pubmed/33154383
http://dx.doi.org/10.1038/s41467-020-19435-z

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