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Deep learning approach for predicting functional Z-DNA regions using omics data

Computational methods to predict Z-DNA regions are in high demand to understand the functional role of Z-DNA. The previous state-of-the-art method Z-Hunt is based on statistical mechanical and energy considerations about B- to Z-DNA transition using sequence information. Z-DNA CHiP-seq experiment re...

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Detalles Bibliográficos
Autores principales: Beknazarov, Nazar, Jin, Seungmin, Poptsova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644757/
https://www.ncbi.nlm.nih.gov/pubmed/33154517
http://dx.doi.org/10.1038/s41598-020-76203-1