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Chi hotspot control of RecBCD helicase-nuclease by long-range intramolecular signaling

Repair of broken DNA by homologous recombination requires coordinated enzymatic reactions to prepare it for interaction with intact DNA. The multiple activities of enterobacterial RecBCD helicase-nuclease are coordinated by Chi recombination hotspots (5′ GCTGGTGG 3′) recognized during DNA unwinding....

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Detalles Bibliográficos
Autores principales: Amundsen, Susan K., Taylor, Andrew F., Smith, Gerald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644769/
https://www.ncbi.nlm.nih.gov/pubmed/33154402
http://dx.doi.org/10.1038/s41598-020-73078-0